Research

Scientific research publications from other websites.


Publications on Major Findings By Health Outcomes
ACE Study publications link adverse childhood experiences to a range of health outcomes.
Each of the following topics will link you to publications which include that outcome as a major finding:
http://www.ncbi.nlm.nih.gov/pubmed/11991154?dopt=Abstract

Dr. Arthur Janov's Primal Center
http://www.primaltherapy.com/

Janov's Refelctions on the Human Condition
http://cigognenews.blogspot.com/


Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood

Leukocyte telomere length (LTL) is a predictor of age-related disease onset and mortality. The association in adults of psychosocial stress or stress biomarkers with LTL suggests telomere biology may represent a possible underlying mechanism linking stress and health outcomes. It is, however, unknown whether stress exposure in intrauterine life can produce variations in LTL, thereby potentially setting up a long-term trajectory for disease susceptibility.
more: http://www.pnas.org/content/108/33/E513.full


Childhood Maltreatment Predicts Unfavorable Course of Illness and Treatment Outcome in Depression: A Meta-Analysis

Results: A meta-analysis of 16 epidemiological studies (23,544 participants) suggested that childhood maltreatment was associated with an elevated risk of developing recurrent and persistent depressive episodes (odds ratio=2.27, 95% confidence interval [CI]=1.80–2.87). A meta-analysis of 10 clinical trials (3,098 participants) revealed that childhood maltreatment was associated with lack of response or remission during treatment for depression (odds ratio=1.43, 95% CI=1.11–1.83). Meta-regression analyses suggested that the results were not significantly affected by publication bias, choice of outcome measure, inclusion of prevalence or incidence samples, study quality, age of the sample, or lifetime prevalence of depression.
Conclusions: Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression.
more: http://ajp.psychiatryonline.org/cgi/content/abstract/appi.ajp.2011.11020335v1

Uher said that the findings could help in the care of people with mental illness. "Whilst we still do not know exactly what type of treatment may improve the care of maltreated individuals, it may be that new treatments based on the biological vulnerabilities associated with childhood maltreatment could prove an exciting avenue for research." could help doctors develop new methods tailored to their "biological vulnerabilities."
Article: http://www.guardian.co.uk/society/2011/aug/15/depression-childhood-abuse-maltreatment


Association of Childhood Adversities and Early-Onset Mental Disorders With Adult-Onset Chronic Physical Conditions

A history of 3 or more childhood adversities was independently associated with onset of all 6 physical conditions (hazard ratios, 1.44 to 2.19). Controlling for current mental disorder made little difference to these associations. Early-onset mental disorders were independently associated with onset of 5 physical conditions (hazard ratios, 1.43 to 1.66).

more: http://archpsyc.ama-assn.org/cgi/content/abstract/68/8/838


Epigenetics and stress
Baby blues


A mother’s stress while she is pregnant can have a long-lasting effect on her children’s genes

RESEARCHERS have known for years that children whose mothers were chronically stressed during pregnancy—by famine, anxiety, the death of a relative or marital discord, for instance—show higher-than-normal rates of various psychological and behavioural disorders when they are adults. They have also known for a long time that those brought up in abusive environments often turn out to be abusive themselves. The second of these observations is usually put down to learning. The reason for the first has remained unclear. A study just published by Axel Meyer, Thomas Elbert and their colleagues at the University of Konstanz in Germany, however, points to a phenomenon called epigenetics
as the likely answer. And if Drs Meyer and Elbert are right, it also suggests an alternative explanation for the inheritance of abusiveness.
Epigenetics is a type of gene regulation that can be passed from a cell to its daughters.
The most common mechanism is methylation. This attaches methyl groups (a carbon atom and three hydrogens) to either adenine or cytosine, two of the four chemical bases that form the alphabet of DNA, depending on the gene involved. The consequence is to inactivate the gene being methylated.
more


Transgenerational impact of intimate partner violence
on methylation in the promoter of the glucocorticoid receptor

KM Radtke1,2,4, M Ruf1,4, HM Gunter2,3,4, K Dohrmann1, M Schauer1, A Meyer2 and T Elbert1
Prenatal exposure to maternal stress can have lifelong implications for psychological function, such as behavioral problems and even the development of mental illness. Previous research suggests that this is due to transgenerational epigenetic programming of genes operating in the hypothalamic–pituitary–adrenal axis, such as the glucocorticoid receptor (GR). However, it is not known whether intrauterine exposure to maternal stress affects the epigenetic state of these genes beyond infancy. Here, we analyse the methylation status of the GR gene in mothers and their children, at 10–19 years after birth. We combine these data with a retrospective evaluation of maternal exposure to intimate partner violence (IPV). Methylation of the mother’s GR gene was not affected by IPV. For the first time, we show that methylation status of the GR gene of adolescent children is influenced by their mother’s experience of IPV during pregnancy. As these sustained epigenetic modifications are established in utero, we consider this to be a plausible mechanism by which prenatal stress may program adult psychosocial function.
more


Fascination violence: on mind and brain of man hunters
Thomas Elbert • Roland Weierstall •
Maggie Schauer

Abstract
Why are savagery and violence so omnipresent among humans? We suggest that hunting behaviour is fascinating and attractive, a desire that makes temporary deprivation from physical needs, pain, sweat, blood and, ultimately, the willingness to kill tolerable and even appetitive. Evolutionary development into the ‘‘perversion’’ of the urge to hunt humans, that is to say the transfer of this hunt to members of one’s own species, has been nurtured by the resultant advantage of personal and social power and dominance. While a breakdown of the inhibition towards intra-specific killing would endanger any animal species, controlled inhibition was enabled in humans in that higher regulatory systems, such as frontal lobe-based executive functions, prevent the involuntary derailment of hunting behaviour. If this control—such as in child soldiers for example—is not learnt, then brutality towards humans remains fascinating and appealing. Blood must flow in order to kill. It is hence an appetitive cue as is the struggling of the victim. Hunting for men, more rarely for women, is fascinating and emotionally arousing with the parallel release of testosterone, serotonin and endorphins, which can produce feelings of euphoria and alleviate pain.
Bonding and social rites (e.g. initiation) set up the constraints for both hunting and violent disputes. Children learn which conditions legitimate aggressive behaviour and which not. Big game hunting as well as attack of other communities is more successful in groups—men also perceive it as more pleasurable. This may explain the fascination with gladiatorial combat, violent computer games but as well ritualized forms like football.
read


Abuse victims struggle with mental health problems

Drug addiction, alcoholism and male prostitution.
For John Swales, a sex abuse victim of Barry Glendinning, the fallout was almost instant after the priest was arrested. Many victims remain at the same maturity level as the age when they were abused.
more: http://www.windsorstar.com/news/Abuse+victims+struggle+with+mental+health+problems/5148483/story.html


How domestic abuse can scar an unborn child for life

High levels of stress during pregnancy can cause an unborn child to have lifelong mental scars, according to researchers.

They believe a mother facing unnecessary crises can leave an imprint in the brains of her children, making them less able to cope as they get older. The gene – called the glucocorticoid receptor – is involved in the brain’s response to stress. The German researchers found that the gene was far less active in children whose mothers were victims of domestic abuse when they were pregnant. Abuse after pregnancy did not appear to affect the way the gene responded in the brains of their children.

Helen Gunter, of the University of Konstanz, said: ‘It changes the way that people respond to stress and they may have a reduced ability to respond to stress.
Past studies have shown that children who have abused parents are more prone to depression later in life.’ Dr Gunter, who reported the findings in the journal Translational Psychiatry, said the study looked only at the extreme stress caused by partner violence.
more: http://www.dailymail.co.uk/health/article-2016452/Babies-born-stressed-mothers-struggle-emotional-scars-life.html


Are Sex Offenders Treatable? A Research Overview
Linda S. Grossman, Ph.D., Brian Martis, M.D. and Christopher G. Fichtner, M.D.

RESULTS: Although rigorous research designs are difficult to achieve, studies comparing treated and untreated sex offenders have been done. Measurement of outcome is flawed, with recidivism rates underestimating actual recurrence of the pathological behavior. Outcome research suggests a reduction in recidivism of 30 percent over seven years, with comparable effectiveness for hormonal and cognitive-behavioral treatments. Institutionally based treatment is associated with poorer outcome than outpatient treatment, and the nature of the offender's criminal record is an important prognostic factor. CONCLUSIONS: Although treatment does not eliminate sexual crime, research supports the view that treatment can decrease sex offense and protect potential victims. However, given the limitations in scientific knowledge and accuracy of outcome data, as well as the potential high human costs of prognostic uncertainty, any commitment to a social project substituting treatment for imprisonment of sexual aggressors must be accompanied by vigorous research.

Problems in sex offender research
Assessment
One of the most difficult issues in the treatment of sex offenders is how to measure improvement. Investigators have not identified a standardized measurement technique that they agree can reliably and validly measure the frequency of sex offenses.
Sex offenders' self-reports or significant others' reports are not reliable indexes of recidivism (10,11). Arrest records underreport sexual offenses (5,12,13); the vast majority of sexual offenses, estimated at greater than 93 percent, are never reported to the police, and fewer than 1 percent of sex offenders are arrested (14). Even fewer are convicted. Arrest and conviction records are also affected by administrative policies that determine which subjects are hospitalized rather than incarcerated. Furthermore, many sex offenders plea bargain—that is, they plead guilty to lesser charges of crimes that are not sexual offenses.
more: http://ps.psychiatryonline.org/cgi/content/full/50/3/349#ABS


The Link Between Adrenal Fatigue and DNA Methylation

Published: Townsend Letter for Doctors & Patients - May 2005

Editor:
Adrenal function is vital to life: without cortisol we die. This fact has been known since the 1930s when it was described by Banting and Best.
Glucocorticords are essential for maintaining carbohydrate, protein and fat metabolism.
They also have a permissive effect which allows for glucagon and catecholamines to work.
Important glucocorticoid effects include the normal functioning of the nervous system, water metabolism, vascular reactivity, regulation of circulating lymphocytes and the immune system and resistance to stress. Complete lack ofadrenal function is a disease state known as Addison's Disease. It is an autoimmune disease usually, caused by antibodies that attack the adrenal gland.
Conventional medicine only recognizes two states: you either make cortisol or you don't. Allopathic physicians are unaware of the decline in adrenal function as illness becomes chronic.
continue: http://www.susansolomonmd.com/adrenal_article.html


Wounds That Time Won’t Heal: The Neurobiology of Child Abuse

Martin H. Teicher

Neuropsychologist Teicher reveals the alarming connections scientists are discovering between child abuse—even when it is psychological, not physical—and permanent debilitating changes in the brain that may lead to psychiatric problems. The discoveries are a wake-up call for our society, but they may also hold hope for new treatments for abused children and the adults that they become.
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Inside the Mind of a Psychopath

The word “psychopath” conjures up movie images of brutal, inexplicable violence:
Jack Nicholson chasing his family with an ax in The Shining or Anthony Hopkins as Hannibal Lecter, his face locked into an armored mask to keep him from biting people to death.

But real life offers another set of images, that of killers making nice: Ted Bundy as law student and aide to the governor of Washington State, and John Wayne Gacy as the Junior Chamber of Commerce’s “Man of the Year.” Psychopaths
are likable guys when they want to be.
continue: http://www.themindinstitute.org/docs/kiehl_buckholtz_sam0910022_final.pdf


Sexually Abused Children at Risk for Adult Psychosis

A new report suggests children who are sexually abused may be at higher risk for developing schizophrenia and other psychotic disorders.

The Austrian study found that a history of sexual abuse with penetration especially increased the risk. (A)

Previous studies have established that abused children are more likely to develop depression, anxiety, substance abuse, borderline personality disorder, post-traumatic stress disorder and suicidal behavior, according to background information in the article.
continue: http://psychcentral.com/news/2010/11/04/sexually-abused-children-at-risk-for-adult-psychosis/20535.html


The latest Mayo-Clinic study conclusion to:

“Sexual Abuse and Lifetime Diagnosis of Psychiatric Disorders: Systematic Review and Meta-analysis”

Abstract:
OBJECTIVE: To systematically assess the evidence for an association between sexual abuse and a lifetime diagnosis of
psychiatric disorders.

There was a statistically significant association between sexual abuse and a lifetime diagnosis of anxiety disorder
(OR, 3.09; 95% CI, 2.43-3.94), depression (OR, 2.66; 95% CI, 2.14-3.30), eating disorders (OR, 2.72; 95% CI, 2.04-3.63),
posttraumatic stress disorder (OR, 2.34; 95% CI, 1.59-3.43), sleep disorders (OR, 16.17; 95% CI, 2.06-126.76), and suicide attempts (OR, 4.14; 95% CI, 2.98-5.76).
Associations persisted regardless of the victim's sex or the age at which abuse occurred.
There was no statistically significant association between sexual abuse and a diagnosis of schizophrenia or somatoform disorders. No longitudinal studies that assessed bipolar disorder or obsessive-compulsive disorder were found.
Associations between sexual abuse and depression, eating disorders, and posttraumatic stress disorder were strengthened by a history of rape.

CONCLUSION: A history of sexual abuse is associated with an increased risk of a lifetime diagnosis of multiple psychiatric disorders.
continue: http://www.mayoclinicproceedings.com/content/85/7/618.abstract?etoc

Video research introduction: http://www.scivee.tv/node/18244

Characteristics of Studies Included in Review:
http://www.mayoclinicproceedings.com/content/suppl/2010/05/10/mcp.2009.0583.DC1/Chen_eAppendix.pdf


Sexual Abuse

Elizabeth ODDONE Paolucci A1, Mark L. Genuis A1, Claudio Violato A2

A1 National Foundation for Family Research and Education, Calgary, Canada
A2 Department of Applied Psychology, University of Calgary, Canada

Abstract:
A meta-analysis of the published research on the effects of child sexual abuse (CSA) was undertaken for 6 outcomes: posttraumatic stress disorder (PTSD), depression, suicide, sexual promiscuity, victim-perpetrator cycle, and poor academic performance.
Thirty-seven studies published between 1981 and 1995 involving 25,367 people were included.
Many of the studies were published in 1994 (24; 65%), and most were done in the United States (22; 59%).
All six dependent variables were coded, and effect sizes (d) were computed for each outcome.
Average unweighted and weighted ds for each of the respective outcome variables were .50 and .40 for PTSD, .63 and .44 for depression, .64 and .44 for suicide, .59 and .29 for sexual promiscuity, .41 and .16 for victim-perpetrator cycle, and .24 and .19 for academic performance. A file drawer analysis indicated that 277 studies with null ds would be required to negate the present findings. The analyses provide clear evidence confirming the link between CSA and subsequent negative short- and long-term effects on development. There were no statistically significant differences on ds when various potentially mediating variables such as gender, socioeconomic status, type of abuse, age when abused, relationship to perpetrator, and number of abuse incidents were assessed. The results of the present meta-analysis support the multifaceted model of traumatization rather than a specific sexual abuse syndrome of CSA.
more: http://heldref-publications.metapress.com/app/home/contribution.asp?referrer=parent&backto=issue,2,10;journal,58,82;linkingpublicationresults,1:119938,1


Early life stress can result in behavioural problems: Study

November 9th, 2009

London, November 09 (ANI): Early life trauma and stress can result in behavioural problems, according to a new study in mice.

Christopher Murgatroyd, a scientist from the Max Planck Institute of Psychiatry in Munich, Germany, who led the study,
briefed that the stressed mice produced hormones that “changed” their genes, to affect their long-term behavioural “programme.”

The researchers had to cause stress to newborn mice to observe the affect on them throughout their lives.
“We separated the pups from their mothers for three hours each day for ten days,” the BBC News quoted Murgatroyd as saying. He added: “It was a very mild stress and the animals were not affected at a nutritional level, but they would [have felt] abandoned.”
It was found that those mice “abandoned” early on in their lives had become less able to cope with stressful situations and also had poorer memories.
Murgatroyd said that these results were because of “epigenetic changes”, meaning the alteration in the DNA of some of the animals’ genes.
Murgatroyd said: “This is a two-step mechanism.”
continue: http://www.thaindian.com/newsportal/health/early-life-stress-can-result-in-behavioural-problems-study_100272030.html


Dynamic DNA methylation programs persistent adverse effects of early-life stress

Chris Murgatroyd , Alexandre V Patchev , Yonghe Wu , Vincenzo Micale , Yvonne Bockm|[uuml]|hl ,
Dieter Fischer , Florian Holsboer , Carsten T Wotjak , Osborne F X Almeida & Dietmar Spengler

Abstract
Adverse early life events can induce long-lasting changes in physiology and behavior. We found that early-life stress (ELS) in mice caused enduring hypersecretion of corticosterone and alterations in passive stress coping and memory.
This phenotype was accompanied by a persistent increase in arginine vasopressin (AVP) expression in neurons of the hypothalamic paraventricular nucleus and was reversed by an AVP receptor antagonist. Altered Avp expression was associated with sustained DNA hypomethylation of an important regulatory region that resisted age-related drifts in methylation and centered on those CpG residues that serve as DNA-binding sites for the methyl CpG–binding protein
2 (MeCP2). We found that neuronal activity controlled the ability of MeCP2 to regulate activity-dependent transcription
of the Avp gene and induced epigenetic marking. Thus, ELS can dynamically control DNA methylation in postmitotic neurons to generate stable changes in Avp expression that trigger neuroendocrine and behavioral alterations that are frequent features in depression.
http://www.nature.com/neuro/journal/v12/n12/pdf/nn.2436.pdf


Researchers find genetic link between physical pain and social rejection (A)
By Stuart Wolpert
| 8/17/2009 9:15:00 AM
CLA psychologists have determined for the first time that a gene linked with physical pain sensitivity is associated with
social pain sensitivity as well.

Their study indicates that variation in the mu-opioid receptor gene (OPRM1), often associated with physical pain, is related to how much social pain a person feels in response to social rejection. People with a rare form of the gene are more sensitive to rejection and experience more brain evidence of distress in response to rejection than those with the more common form.

The research was published Aug. 14 in the early online edition of Proceedings of the National Academy of Sciences and
will appear in the print version in the coming weeks.

The findings give weight to the common notion that rejection "hurts" by showing that a gene regulating the body's
most potent painkillers — mu-opioids — is involved in socially painful experiences too, said study co-author Naomi Eisenberger, UCLA assistant professor of psychology and director of UCLA's Social and Affective Neuroscience Laboratory.
more at: http://newsroom.ucla.edu/portal/ucla/a-genetic-link-between-pain-and-98593.aspx


Posttraumatic Stress Disorder in Abused and Neglected Children Grown Up
Cathy Spatz Widom, Ph.D.

OBJECTIVE: The purpose of this study was to describe the extent to which childhood abuse and neglect increase a person's risk for subsequent posttraumatic stress disorder (PTSD) and to determine whether the relationship to PTSD persists despite controls for family, individual, and lifestyle characteristics associated with both childhood victimization and PTSD.
METHOD: Victims of substantiated child abuse and neglect from 1967 to 1971 in a Midwestern metropolitan county area were matched on the basis of age, race, sex, and approximate family socioeconomic class with a group of nonabused and nonneglected children and followed prospectively into young adulthood. Subjects (N=1,196) were located and administered a 2-hour interview that included the National Institute of Mental Health Diagnostic Interview Schedule to assess PTSD.
RESULTS: Childhood victimization was associated with increased risk for lifetime and current PTSD.

More at: Am J Psychiatry 156:1223-1229, August 1999
© 1999 American Psychiatric Association http://ajp.psychiatryonline.org/cgi/content/abstract/156/8/1223


Antisocial personality disorder in abused and neglected children grown up
BK Luntz and CS Widom
University at Albany School of Criminal Justice, NY 12222.

OBJECTIVE: the authors' goal in this study was to examine the extent to which having been abused and/or neglected
in childhood raises a person's risk for having an adult DSM-III-R diagnosis of antisocial personality disorder.
METHOD: Children who had experienced substantiated child abuse and/or neglect from 1967 to 1971 in a Midwestern metropolitan county area were matched on the basis of age, race, sex, and approximate family social class with a group of nonabused and nonneglected children and followed prospectively into young adulthood. Subjects were located and participated in a 2-hour interview consisting of a series of structured and semistructured questions, rating scales, and a psychiatric assessment using the National Institute of Mental Health Diagnostic Interview Schedule.
Interviews were completed with 699 young adult subjects (416 abused and/or neglected and 283 comparison subjects).
RESULTS: Childhood victimization was a significant predictor of the number of lifetime symptoms of antisocial personality disorder and of a diagnosis of antisocial personality disorder, despite the fact that controls for demographic characteristics and arrest history were introduced.
CONCLUSIONS: These findings suggest the importance of inquiring about a patient's childhood history of abuse and/or neglect when antisocial symptoms are evident. In addition to speculation about a possible saturation model for the consequences of childhood victimization, these findings also reinforce a multiple causation model of antisocial personality disorder.
Am J Psychiatry 1994; 151:670-674
Copyright © 1994 by American Psychiatric Association http://ajp.psychiatryonline.org/cgi/content/abstract/151/5/670


Is Abuse during Childhood a Risk Factor for Developing Substance Abuse Problems as an Adult?
BENNETT, ELIZABETH M. B.S.; KEMPER, KATHI J. M.D., M.P.H.
Abstract
The purpose of this study was to evaluate the relationship between a history of childhood physical abuse and later substance abuse, controlling for family history of substance abuse. The study was a cross-sectional survey.
Subjects were a convenience sample of mothers with children younger than 6 years being seen for routine care in five pediatric clinics. Mothers were given an anonymous, self-administered questionnaire on demographics, substance abuse, history of physical abuse, and family history of substance abuse. Of the 733 respondents, 24% reported having been physically abused, 24% reported a family history of substance abuse, and 36% had a positive screen for substance abuse.
A positive screen for substance abuse was more common among those who reported having been abused than those who had not (47% vs 32%, p < .001). After controlling for family history of substance abuse, a history of being abused remained significantly associated with current substance abuse (odds ratio = 1.58, 95% confidence interval 1.1, 2.2).
Suffering abuse during childhood is a significant risk factor for later substance abuse, even after controlling for a family history of substance abuse. Clinicians treating victims of abuse may wish to include substance abuse prevention measures.
J Dev Behav Pediatr 15:426-429, 1994. Index terms: alcohol abuse, drug abuse, child abuse.
(C) Lippincott-Raven Publishers.http://journals.lww.com/jrnldbp/Abstract/1994/12000/Is_Abuse_during_Childhood_a_Risk_Factor_for.6.aspx


Developmental traumatology: a contributory mechanism for alcohol and substance use disorders

References and further reading may be available for this article. To view references and further reading you must purchase this article.

Michael D. De Bellis

University of Pittsburgh Medical Center, Developmental Traumatology Laboratory, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA

Abstract
Early childhood traumatic experiences, such as childhood maltreatment, are associated with an enhanced risk of adolescent and adult alcohol and substance use disorders (defined as DSM-IV alcohol or substance abuse or dependence).
Maltreated children and adolescents manifest dysregulation of major biological stress response systems including adverse influences on brain development. Dysregulation of biological stress response systems may lead to an enhanced
vulnerability for psychopathology, particularly posttraumatic stress disorder (PTSD) and depression. These negative affect disorders may put a child at increased risk for adolescent or young adult onset alcohol or substance use disorders. Thus, studies in developmental traumatology may prove to be critical in the effort to attempt to link the neurobiology of maltreatment-related PTSD with the neurobiology of alcohol and substance use disorders and in developing early strategies for the prevention of adolescent and adult alcohol and substance use disorders.
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On the Corrective Emotional Experience
In the era of Freud and psychoanalysis the linchpin of the therapy was the analysis of transference:
how the patient responds to the doctor and (counter transference) how the doctor reacts to the patient.
The whole idea was to change the patient through a corrective emotional relationship. Helping her to be more independent, not rely for advice or love and guidance from the doctor. Now decades later, that notion of the corrective emotional experience has gained many adherents. It is still in essence the analysis of transference.
http://cigognenews.blogspot.com/2009/04/on-corrective-emotional-experience.html


Social support and oxytocin interact to suppress cortisol
and subjective responses to psychosocial stress

BACKGROUND: The presence of social support has been associated with decreased stress responsiveness.
Recent animal studies suggest that the neuropeptide oxytocin is implicated both in prosocial behavior and in the central nervous control of neuroendocrine responses to stress. This study was designed to determine the effects of social support and oxytocin on cortisol, mood, and anxiety responses to psychosocial stress in humans.
more: http://www.oxytocin.org/oxy/socialsupport.html


Birth and Sex: How They Are Related
Anoxia, Reduced Oxygen at Birth and Adult Behavior...
Dr. Arthur Janov
Oxytocin (Part 1/5): http://cigognenews.blogspot.com/2009/03/oxytocin-part-15_14.html
Oxytocin (Part 2/5): http://cigognenews.blogspot.com/2009/03/oxytocin-part-25.html
Oxytocin (Part 3/5): http://cigognenews.blogspot.com/2009/03/oxytocin-part-35.html
Oxytocin (Part 4/5): http://cigognenews.blogspot.com/2009/04/oxytocin-part-45.html
Oxytocin (Part 5/5): http://cigognenews.blogspot.com/2009/04/oxytocin-part-55.html


Epigenetic Effects of Childhood Abuse Found in Adults

Researchers at McGill University in Montreal have discovered that adult males who were the victims of significant physical and/or sexual abuse as children carried a genetic imprint of that abuse into adulthood. One group studied had committed suicide as adults, while another group consisted of suicides but without childhood abuse.
A third group apparently consisted of living adults who had suffered no abuse.

Men with significant childhood abuse showed chemical markers on the glucocorticoid gene receptor which mediates stress responses in the brain. Researchers called the finding "quite significant." Childhood abuse can "literally affect the genome and its operation," according to researcher Michael Meaney.
More: http://mensnewsdaily.com/glennsacks/2009/03/03/epigenetic-effects-of-childhood-abuse-found-in-adults/

Epigenetic additional information: http://cigognenews.blogspot.com/2008/07/inheritance-of-acquired-characteristics.html


Beta-blockers erase emotion of fearful memories
Memory remains, but feeling of fear is less or gone, shows experimental study in people

The first experimental study in humans connecting beta-blockers and memory suggests these drugs, usually taken to treat heart conditions, can also wipe away the emotions associated with frightening memories, according to a study published online February 15 in Nature Neuroscience. The power of such memories could be dampened when a person thinks about the traumatic events after taking the drugs, the scientists say. (A)
more: http://www.sciencenews.org/view/generic/id/40928/title/Beta-blockers_erase_emotion_of_fearful_memories


Thirty-Year Study Links Neuroscience, Specific Trauma,
PTSD, Image Conversion, and Language Translation

Dee Spring, Ventura, CA
Abstract
Despite voluminous literature on trauma, studies on specific trauma and art expression remain sparse.
Recurring graphic forms produced by sexual abuse victims have appeared in art therapy publications dating back to Naumburg (1958), but links between sexual abuse-assault and recurring graphic forms were not considered. In 1973, this author began a 30-year study of recurring graphic forms in drawings by this incidentspecific group. Results reveal victims produce an artistic language not produced by nonvictims. Analyses using repeated ANOVAS determined frequency of occurrence of graphic forms across 225 drawings of 45 adult females. Findings indicate distinct graphic forms symbolize sensory-perceptual elements and stimulate integration of traumatic effects by image conversion through language translation, artistic to linguistic. (A)
More: http://eric.ed.gov/ERICWebPortal/custom/portlets/recordDetails/detailmini.jsp?_
nfpb=true&_&ERICExtSearch_SearchValue_0=EJ682604&ERICExtSearch_SearchType_0=no&accno=EJ682604


Single Brain Cell Can Store Memory
US scientists studying brain cells in mice found that a single cell in the front part of the brain can hold fleeting traces of memories on its own for as long as a minute and perhaps even longer: it behaves a bit like RAM, the short term memory storage used by computers.
Scientists already know that permanent memories get stored when glutamate (an amino acid) switches on ion channels of brain cells to reorganize and strengthen the way they connect to each other.
The study was sponsored by the National Institute on Drug Abuse; National Alliance for Research on Schizophrenia and Depression; the Alexander S. Onassis Public Benefit Foundation; and the Department of Veterans Affairs.
more: http://www.medicalnewstoday.com/articles/136628.php


Cortisol and Imaginal Exposure in Posttraumatic Stress

Imaginal exposure is closely associated with hippocampal processing of traumatic memory. The hippocampus is a target for glucocorticoids which influence memory retrieval and stress response. Glucocorticoid secretion in response to imaginal exposure has not been investigated. We measured subjective distress and salivary cortisol during the 1st and the 20th exposure session in a patient with PTSD. Despite considerable arousal and anxiety, cortisol did not increase during the first exposure. During the 20th exposure there was a marked reduction of distress, although cortisol values did not differ from exposure 1. The response of glucocorticoids to imaginal exposure and mechanisms of the lacking cortisol response need further research (German J Psychiatry 2002;5:75-77).
more: http://www.gjpsy.uni-goettingen.de/gjp-article-otte.pdf or


Science News
Pain Hurts More If Person Hurting You Means It
ScienceDaily (Dec. 20, 2008) — Researchers at Harvard University have discovered that our experience of pain depends on whether we think someone caused the pain intentionally. In their study, participants who believed they were getting an electrical shock from another person on purpose, rather than accidentally, rated the very same shock as more painful. Participants seemed to get used to shocks that were delivered unintentionally, but those given on purpose had a fresh sting every time.

Improved Foster Care Reduces Risk Of Adult Mental And Physical Illness, Study Finds

ScienceDaily (June 6, 2008) — In the first controlled follow-up study ever to examine the long-term health effects of foster care programs, researchers from Harvard Medical School showed that the extremely high rates of mental and physical
disorders typically found among adult alumni of public foster care programs were significantly reduced among alumni of a private foster care program staffed by highly trained social workers with low caseloads and good access to quality services.
originaly published by: http://www.sciencedaily.com/releases/2008/06/080602160721.htm


Coming Apart: Trauma and the Fragmentation of the Self
http://www.dana.org/news/cerebrum/detail.aspx?id=11122
By David Spiegel, M.D.
About David Spiegel, M.D.
January 31, 2008
The controversial diagnosis of dissociative identity disorder (DID) has replaced what once was called "multiple personality disorder." People diagnosed with DID have trouble integrating their memories, sense of identity, and aspects of consciousness into a unified whole. New research supports the diagnosis and sheds light on what may have gone wrong in patients' brains, suggests David Spiegel, M.D. Spiegel, who chaired the professional working group that recommended the change of name in psychiatry's principle diagnostic manual, notes that the disorder likely stems from trauma and can be considered a severe form of post-traumatic stress disorder. Among the biological markers he describes are a smaller hippocampus and certain neurotransmitters. A better understanding of the importance of specific regions of the brain to memory and emotion may help push research forward. (A)


Running head: Brain changes in posttraumatic stress disorder
Current Directions in Psychology (in press)

Structural and functional neuroplasticity in relation to traumatic stress
Iris-Tatjana Kolassa, Thomas Elbert
Clinical Psychology & Neuropsychology, University of Konstanz, Germany
Abstract
The body’s stress response is an essential adaptive and protective mechanism to cope with threatening situations. However, chronic or traumatic stress leads to neuroplastic changes involving structural and functional alterations in the traumatized brain. We argue for a building block effect: exposure to different traumatic event types increases the probability of developing posttraumatic stress disorder (PTSD), via incremental enlargement of a fear network. Evidence on neuroplastic changes in PTSD is summarized, including recent results from research on animal models of stress-related neuroplastic remodeling, with an emphasis on structural and functional changes in the hippocampus, the amygdala, and the medial prefrontal cortex.


Antidepressants and alternative treatments for depression
by Marcelle Pick, OB/GYN NP
http://www.womentowomen.com/depressionanxietyandmood/antidepressants.asp
Jackie was just 42 when she came to Women to Women for help. She had gone to her prior healthcare provider complaining of fatigue and “feeling low” two weeks out of every month. She had two active children, kept house, helped her husband with his business, and cared for her aging parents. No wonder Jackie was tired. But her doctor put her on Prozac.
....Certain chronic pain conditions that primarily affect women, such as fibromyalgia, endometriosis and rheumatoid arthritis, can cause mild depression and multiple trips to the doctor’s office. While your primary care doctor may be unable to resolve your chronic pain, he or she can help make you happier about living with it. If they can satisfy you and the HMO with a prescription, they feel they’ve done their job.
....While doctors are under pressure from the managed care system on the one hand, the influence of the pharmaceutical companies who make antidepressants is truly pervasive.


Low Cortisol Levels May Predict PTSD Risk
From Cathleen Henning Fenton,
Your Guide to Panic Disorder.

About.com Health's Disease and Condition content is reviewed by our Medical Review Board Researchers at the Veterans Affairs Medical Center (VAMC) in Bronx, NY, have been studying post-traumatic stress disorder (PTSD) in children of Holocaust survivors. A major conclusion of these studies is that these children have a higher risk of developing PTSD than other people. In a study presented in the August 2000 The American Journal of Psychiatry, the research group discovered that adult children with at least one parent who is a Holocaust survivor have low cortisol levels. The discovery could mean that low cortisol levels may be predictive of the development of PTSD.
Cortisol is a hormone that scientists associate with stress as well as chronic mood disorders. During times of stress, cortisol levels rise and then subside as the stress subsides. If stress is chronic or if a chronic mood disorder (anxiety, depression) is present, increased cortisol levels may indicate that the brain has become resistant to cortisol's effects, scientists believe.
read more


Study links sexual abuse with obesity
Trauma may up weight gain
BY PEGGY O'FARRELL | POFARRELL@ENQUIRER.COM
http://news.enquirer.com/apps/pbcs.dll/article?AID=/20070730/NEWS01/707300371/1056/COL02
Young women who were sexually abused as children are more likely to be obese than women who weren't abused, a new study finds.
One group of 84 girls had been sexually abused; the second group of 89 had not. Both groups included girls from similar
economic, ethnic and racial backgrounds. (A)


Researchers find protein that might reinforce people's fears

Boston Globe July 16, 2007
http://www.boston.com/news/globe/health_science/articles/2007/07/16/researchers_find_protein_that_might_reinforce_peoples_fears/

From post-traumatic stress disorder to fear of heights, millions of Americans suffer from what scientists call contextual
fear -- an emotional response tied to a specific life experience. (A)


A hippocampal Cdk5 pathway regulates extinction of contextual fear
Published online: 15 July 2007; | doi:10.1038/nn1943
http://www.nature.com/neuro/journal/vaop/ncurrent/abs/nn1943.html

Treatment of emotional disorders involves the promotion of extinction processes, which are defined as the learned reduction of fear.
more


Effect of post-retrieval propranolol on psychophysiologic responding during subsequent
script-driven traumatic imagery in post-traumatic stress disorder.

Brunet A, Orr SP, Tremblay J, Robertson K, Nader K, Pitman RK.

Department of Psychiatry, McGill University and Douglas Hospital Research Center, Montreal, QC, Canada.

The beta-adrenergic blocker propranolol given within hours of a psychologically traumatic event reduces physiologic responses during subsequent mental imagery of the event. Here we tested the effect of propranolol given after the retrieval of memories of past traumatic events. Subjects with chronic post-traumatic stress disorder described their traumatic event during a script preparation session and then received a one-day dose of propranolol (n=9) or placebo (n=10), randomized and double-blind. A week later, they engaged in script-driven mental imagery of their traumatic event while heart rate, skin conductance, and left corrugator electromyogram were measured. Physiologic responses were significantly smaller in the subjects who had received post-reactivation propranolol a week earlier. Propranolol given after reactivation of the memory of a past traumatic event reduces physiologic responding during subsequent mental imagery of the event in a similar manner to propranolol given shortly after the occurrence of a traumatic event.

PMID: 17588604 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/sites/entrez?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=17588604&dopt=Abstract


The Influence of Organized Violence and Terror on the brain and Mind: A Co-Constructive Perspective.
Thomas Elbert, Brigitte Rockstroh, Iris-Tatjana Kolassa, Maggie Schauer, and Frank Neuner

Abstract:
The human brain is formed by two interactive systems the genetic-biological and the sociocultural system. The brain, in turn, regulates behavior and thereby acts on the societal environment. This chapter examines who experience shapes the brain and describes the interaction of the brain, behavior, and culture under condition of extreme and traumatic stress as present in many of the world war-torn regions. ……..
direct link


Domestic Violence in Australia Leads to Number of Suicides
Health News Posted on May 27, 2007
http://www.medindia.net/news/Domestic-Violence-in-Australia-Leads-to-Number-of-Suicides-21344-1.htm
Advanced countries?

No matter, domestic violence against women continues to be a major scourge.
Burden of Disease and Injury in Australia, a comprehensive report released Saturday, said nearly a third of female suicides in the country could be attributed to domestic violence.

So also 15 per cent of women suffering from depression were those who had been subjected to violence at home.
The report further says that child sexual abuse causes 10 per cent of the anxiety and depression in the entire population.


The International Society for the Study of Trauma & Dissociation

Severe Early Trauma, which examines research on the complex effects of childhood trauma, and the implications for treatment.
http://www.cavalcadeproductions.com/childhood-trauma.html

The ACE Study, which documents the high incidence of childhood trauma and its costly effects on adult physical health, and the implications for medical practice.
http://www.cavalcadeproductions.com/ace-study.html

Legal Issues in Trauma Therapy, which describes the FMS backlash against therapists in the 1990’s, and outlines
standards of care and strategies for prevention.
http://www.cavalcadeproductions.com/false-memory.html

Vicarious Traumatization, which describes the effects of vicarious trauma, or the stress experienced by caregivers, and how to deal with it personally and organizationally.
http://www.cavalcadeproductions.com/vicarious-traumatization.html

Trauma & Memory, which examines how dissociation functions as a defense against overwhelming stress, and how such traumatic memories may be stored.
http://www.cavalcadeproductions.com/bessel-van-der-kolk.html


The Neurobiology of Social Bonds
Professor Keith M Kendrick
The Babraham Institute Cambridge http://neuroendo.org.uk/index.php/content/view/34/11/

When released in the brain through giving birth or mating, the neuropeptides oxytocin and vasopressin are involved in promoting parent-offspring and monogamous bonds in animals such as sheep and voles. Bonds are only formed in species where receptors for these neuropeptides are highly expressed in dopamine-producing reward centres.
In humans, dysfunctions in these same systems can be associated with autism and, when we see people we love,
these systems become activated. (A)


NEUROBIOLOGICAL SEQUELAE OF CHILDHOOD TRAUMA:
Post-traumatic Stress Disorders in Children
Bruce D. Perry, M.D., Ph.D.
The ChildTrauma Academy
www.ChildTrauma.org


The Vortex of Violence
How Children Adapt and Survive in a Violent World
Bruce D. Perry, M.D., Ph.D.
Pre-Final DRAFT
published: http://www.childtrauma.org/CTAMATERIALS/vortex_interd.asp
This booklet is one in a series developed by the ChildTrauma Academy to assist parents, caregivers, teachers and various professionals working with maltreated and traumatized children.
Adapted in part from: "Maltreated Children: Experience, Brain Development and the Next Generation"
(W.W. Norton & Company, New York, in preparation)


Childhood abuse hurts the brain
By William J. Cromie
Gazette Staff http://www.hno.harvard.edu/gazette/2003/05.22/01-brain.html
Abuse during childhood can change the structure and function of a brain, and increase the risk of everything from anxiety to suicide.

"These changes are not limited to physical and sexual abuse; there's growing evidence that even verbal assault can alter the way a developing brain is wired," says Martin Teicher, associate professor of psychiatry at Harvard Medical School. The ominous effects are tied to reduction in the size of sensitive areas of the brain and to abnormal brain waves that mimic epilepsy. (A)


Sexual Abuse of Infants
A five-part question focusing on sexual abuse during infancy.
published: http://www.childtrauma.org/ctamaterials/infant_abuse.asp
Can infants recall sexual abuse later in life?
The key word in this question is "recall." Unfortunately, for most, the concept of memory is limited to the storage and recall of cognitive, narrative memory. In this conceptualization, a pre-verbal infant would not be capable of "remembering" and "recalling" any event. Furthermore, we are all familiar with the developmental amnesia that occurs at approximately age three.


Science News
Week of May 27, 2006; Vol. 169, No. 21 , p. 328

Violent Developments Disruptive kids grow into their behavior
by Bruce Bower

"Violence is such a complicated issue," Twemlow says. "There's always a set of preconditions to violent behavior and never just one cause."

Meyer-Lindenberg, a neuroscientist, directed studies of 142 white adults who had inherited one of two common versions of a gene that triggers production of an enzyme called monoamine oxydase A (MAOA).
That enzyme controls the supply of an important brain chemical. One of the gene variants yields weak MAOA activity in the brain, resulting in elevated concentrations of serotonin. Too much of that chemical messenger upsets the regulation of emotions and impulses.

related articles


Verbal Abuse In Childhood Triggers Adult Anxiety, Depression

A new study by Florida State University researchers has found that people who were verbally abused as children grow up to be self-critical adults prone to depression and anxiety. People who were verbally abused had 1.6 times as many symptoms of depression and anxiety as those who had not been verbally abused and were twice as likely to have suffered a mood or anxiety disorder over their lifetime, according to psychology Professor Natalie Sachs-Ericsson, the study's lead author.


Approach to laws on offenders criticized
By JONATHAN ROOS AND LEE ROOD
REGISTER STAFF WRITERS

Studies show that 80 percent or more of child sexual abuse victims are molested by relatives, family friends or others known to the victims. But new laws that restrict where sex offenders can live or require electronic monitoring of their movements appear aimed at keeping strangers from stalking victims around schoolyards or child-care centers. (A)


Physically abused boys may be more likely to commit domestic violence as adults
A history of childhood physical abuse may be common in men from urban settings, and these men with physical abuse histories may be more likely to commit domestic violence. (A35)
http://www.xagena.it/news/medicinenews_net_news/56921b5830dc422b9e197e0df48c5b8c.html


Abuse worst when unreported
By:Bob Berry, Crime prevention columnist

Sexual abuse of a child or elderly person is probably the most secretive and the hardest type of abuse to detect.
It most often occurs within a family setting with the suspect usually being a parent, relative or caretaker. This type of abuse sometimes can be sheltered for decades until something prompts the victim to reveal his or her story.
In more cases than we would like to believe, someone else within or close to the family is aware of the abuse. I would venture to guess that we all know someone or know of someone's family who has been touched by emotional, physical or sexual abuse. How do we stop the abuse? We have to break the cycle. Children who are abused often grow up to be parents who abuse their children.
(Archive A 34)
Read: http://www.zwire.com/site/news.cfm?BRD=1574&dept_id=532215&newsid=15399587&PAG=461&rfi=9


Abuse Victims Still Suffer Decades Later
ktla 5 - Los Angeles,CA,USA
... were very close." But by the time they were adults, they saw ... know that from the first moment they were abused as boys ... He won't let anyone baby-sit his children. ...
http://ktla.trb.com/news/local/la-me-victims16oct16,0,1290041.story?coll=ktla-news-1


Great information about childhood trauma is available by Dr. Michael Corry.
Sexual Abuse & Hatred of the Self
http://www.depressiondialogues.ie/custom12/His resource page is vital to many Childhood abuse victims.
http://www.depressiondialogues.ie/custom19/


In addition:
How Dr. Michael speaks on behalf of three patients, all victims of layers of abuse, in particular sexual.
Michael Corry's letter to the Irish Times
19 May 2005
http://www.depressiondialogues.ie/custom42/


The Invisible Epidemic: Post-Traumatic Stress Disorder, Memory and the Brain
J. Douglas Bremner, M.D.
Dr. Bremner is a faculty member of the Departments of Diagnostic Radiology and Psychiatry, Yale University School of Medicine, Yale Psychiatric Institute, and National Center for PTSD-VA Connecticut Healthcare System.
The research reviewed in this article was supported by an NIH-sponsored General Clinical Research Center (GCRC)
Clinical Associate Physician (CAP) Award and a VA Research Career Development Award to Dr. Bremner, and the National Center for PTSD Grant.
Post-traumatic Stress Disorder (PTSD) is something of an invisible epidemic. The events underlying it are often mysterious and always unpleasant. It is certainly far more widespread than most people realize. For example, a prime cause of PTSD is childhood sexual abuse. About 16% of American women (about 40 million) are sexually abused (including rape, attempted rape, or other form of molestation) before they reach their 18th birthday.


Female Perpetrators More Common Than Known Previously; Boys Abused Almost As Often As Girls
Wednesday July 6, 3:00 pm ET
Kaiser Permanente Research: Gender and Sexual Abuse
"Childhood sexual abuse (CSA) occurs on a worldwide basis and although most studies on the long-term consequences
of CSA have focused on women, sexual abuse of both boys and girls is prevalent," said Vincent J Felitti, MD, of the Kaiser Permanente, San Diego Medical Center. "An interesting finding of the article is that a significant number of boys were molested by women."


Infant abuse not linked to genetics
Tue 28 Jun 2005 11:59 am CST
CHICAGO (myDNA News)
Reviewed: June 28, 2005 Rick Nauert PhD
Source: Medical News Today
Nine of the 16 females who were abused in infancy by their biological or foster mothers were abusive toward their own offspring, while none of the 15 females reared by non-abusive mothers were abusive toward their offspring.
Arch.Sience2


Egg and Sperm Memory:
Universal Body Movements in Cellular Consciousness and What They Mean
Terry Larimore, L.M.S.W., and Graham Farrant, M.D.
A Key to World Peace in Cellular Consciousness

Cellular consciousness is the complete memory that we each carry in our bodies of our earliest experiences, including conception and the separate experiences of being a sperm and an egg. Research in the field of pre- and perinatal psychology is showing how these early times and experiences influence us in ways that we have never be-fore been aware of, much less understood. It is being shown more and more that we are constantly (unconsciously) and profoundly affected by these experiences in every aspect of our lives.

More about Graham Farrant:
Interviewed by Arnold Buchheimer at Appel Farm, New Jersey Sunday, August 31, 1986
http://www.primal-page.com/farrant.htm


Childhood abuse is associated with a host of neurobiological abnormalities
Martin H. Teicher, M.D., Ph.D. (Independent Investigator 2005) of McLean Hospital/Harvard University Childhood abuse is associated with a host of neurobiological abnormalities including: EEG changes, attenuated maturation of the left hemisphere, as well as structural changes in the corpus callosum, adult hippocampus, and cortex.
originaly published: http://www.narsad.org/research/summaries/teichermartin-2005ii.html


Cortisol and social functioning interact to cause depression
Hypercortisolemia appears to be a predisposing factor for low levels of social functioning, which in turn increases the risk of depression, UK investigators reveal.


Steroid metabolism altered in depressed patients
Altered steroid metabolism has been identified in patients with unipolar recurrent major depression, which investigators say may be the cause as well as a consequence of the disorder.


THE SCANDAL OF SEXUAL MUTILATION (PDF)


PTSD linked to fibromyalgia and MDD
Patients with fibromyalgia, a chronic pain condition of unknown etiology, appear to be at increased risk of post-traumatic stress disorder (PTSD), but only if they have a lifetime history of major depressive disorder (MDD), study findings indicate.


SCIENTIFIC PROOF-ABUSED INFANTS CAN GROW UP TO BE ABUSIVE ADULTS
New evidence proving that children damaged at an early age can grow up to be abusive adult
Proof-Abused Infants Can Be Abusive Adults

Questions and Answers about Memories of Childhood Abuse Can a memory be forgotten and then remembered?
Can a 'memory' be suggested and then remembered as true?
http://www.apa.org/pubinfo/mem.html

Treating Adults Who Were Sexually Abused As Children: Central Principles
By John Briere, Ph.D.
http://www.ncptsd.org/publications/cq/v6/n2/briere.html


Many articles by Dr. James W. Prescott , the infant and child advocate

Rock A Bye Baby
A Time Life Documentary (1970)
The Time Life documentary "Rock A Bye Baby" describes the influence of different practices in infant treatment and child rearing on emotional development, both in humans and in monkeys.



Brain scan to beat the blues - Results show who should use drugs
published by: The Daily Telegraph Sidney Australia


IF VIOLENCE IS LEARNED BEHAVIOR, WHO TEACHES IT?
Many people charge that images in the media, ineffective laws, or weak law enforcement is responsible for violence in our society, but they are unwilling to consider that their own behavior may foster aggression and violence.


IS IT ABUSIVE TO SPANK A CHILD?
Tension exists between the deeply ingrained value that spanking is appropriate and necessary discipline for a child and the psychological knowledge that, if violence is learned behavior, even spankings can teach children that it is okay to use some kinds of violence, even with people they love.


WHY DON'T BATTERED WOMEN JUST TAKE THEIR CHILDREN AND LEAVE?
Many believe that violent abuse can be stopped by simply leaving the home, but research indicates that leaving does not stop the abuse.


IS IT POSSIBLE TO HAVE DELAYED MEMORIES OF BEING SEXUALLY ABUSED AS A CHILD?
Clinical reports suggest that sexual abuse victims may forget the abusive experiences, then remember them later in their lives, but empirical research findings cannot explain this phenomenon by anything we currently know about memory.


HOW MUCH DO EMOTIONS INFLUENCE WHAT PROFESSIONALS KNOW
AND DO ABOUT VIOLENCE IN THE FAMILY?

Service providers and researchers who deal with family violence often feel torn as they try to maintain professional
attitudes and responses at the same time that they feel outrage, disgust, fear, and sadness because of their constant
exposure to personal stories of abuse.


IS ABUSE AN EXCUSE?
Generally people feel compassion for abuse victims, along with understanding and forgiveness for some of their undesirable behaviors, but often those attitudes conflict with the need to hold people personally accountable for their behavior.

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